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CS-W001157 4
Total: USD 88.00

2,6-Dichloro-3-formylpyridine

  • CAS No. 55304-73-9

  • Cat. No. CS-W005448
  • Molecule weight176.00
  • Purity≥96%
  • MDL No.MFCD07369746

*For research and further manufacturing use only, not for direct human use.

2,6-Dichloro-3-formylpyridine|CS-W005448

Structure of 55304-73-9

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General Information

  • CAS No. 55304-73-9
  • Cat. No. CS-W005448
  • Purity ≥96%
  • MDL No. MFCD07369746
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃Cl₂NO
  • Molecular Weight 176.00
  • Synonym(s) 2,6-Dichloropyridine-3-Carboxaldehyde
  • SMILES ClC1=NC(=CC=C1C=O)Cl

Description

2,6-Dichloro-3-formylpyridine features a pyridine core functionalized with two chlorine atoms at the 2 and 6 positions and a formyl group at the 3 position. This electron-deficient heterocycle integrates readily into synthetic scaffolds requiring polar, reactive sites. The formyl moiety enables nucleophilic addition or condensation reactions, while the dichloro substitution enhances electrophilicity and directs downstream functionalization. The compound exhibits stability under standard handling conditions and serves as a key intermediate in pharmaceutical and agrochemical synthesis.

Synthesis

  • Route1
    • In-stock
      2,6-Dichloropyridine|CS-W020060
      2402-78-0
    • null|null
      68-12-2
    • ~60%
    • In-stock
      2,6-Dichloro-3-formylpyridine|CS-W005448
      55304-73-9

    References

    • SUNOVION PHARMACEUTICALS INC.; JONES, Phillip, G.; LEW, Robert; SPEAR, Kerry, L.; XIE, Linghong Patent: WO2013/169964 A1, 2013 ; Location in patent: Paragraph 00254; 00255 ;
  • Route2

    References

    • ELI LILLY AND COMPANY Patent: WO2006/44454 A1, 2006 ; Location in patent: Page/Page column 62 ; WO 2006/044454 A1
  • Route3

    References

    • ANORMED INC. Patent: WO2007/22371 A2, 2007 ; Location in patent: Page/Page column 61-62 ; WO 2007/022371 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H317-H319-H335
Precautionary Statements : P261-P264-P270-P271-P272-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   2.2009
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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