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CS-W001157 4
Total: USD 88.00

(1-Methyl-1H-indol-2-yl)methanamine

  • CAS No. 55556-57-5

  • Cat. No. CS-0151215
  • Purity≥98%
  • MDL No.MFCD06801045
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(1-Methyl-1H-indol-2-yl)methanamine|CS-0151215

Structure of 55556-57-5

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Description

(1-Methyl-1H-indol-2-yl)methanamine features a methylated indole core with a primary amine tethered to the 1-position, delivering a polar, electron-rich scaffold. This configuration enhances solubility and reactivity in synthetic transformations, particularly in coupling reactions and bioconjugation workflows. The molecule exhibits bench-stable handling characteristics under standard conditions, enabling straightforward integration into medicinal chemistry and materials synthesis pipelines.

Application

(1-Methyl-1H-indol-2-yl)methanamine serves as a versatile building block in medicinal chemistry, enabling the synthesis of indole-based pharmaceuticals and bioactive heterocycles. The primary amine functionality facilitates straightforward derivatization via amidation, alkylation, and reductive amination, while the methyl-substituted indole core provides enhanced metabolic stability and favorable pharmacokinetic properties. Bench-stable and readily purified by column chromatography, it functions effectively in standard coupling protocols and supports scalable synthesis of targeted scaffolds.

General Information

  • CAS No. 55556-57-5
  • Cat. No. CS-0151215
  • Purity ≥98%
  • MDL No. MFCD06801045
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂N₂
  • Molecular Weight 160.22
  • Synonym(s) C-(1-Methyl-1H-indol-2-yl)-methylamine
  • SMILES CN1C(=CC2=CC=CC=C21)CN

Computational Chemistry Data

  • TPSA   30.95
  • LogP   1.637
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362+P364-P403+P233-P405-P501

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