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CS-W001157 4
Total: USD 88.00

2-Aminothiazol-4(5H)-one

  • CAS No. 556-90-1

  • Cat. No. CS-W005207
  • Purity≥97%
  • MDL No.MFCD00003186

*For research and further manufacturing use only, not for direct human use.

2-Aminothiazol-4(5H)-one|CS-W005207

Structure of 556-90-1

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General Information

  • CAS No. 556-90-1
  • Cat. No. CS-W005207
  • Purity ≥97%
  • MDL No. MFCD00003186
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₄N₂OS
  • Molecular Weight 116.14
  • Synonym(s) 4(5H)-Thiazolone, 2-amino-
  • SMILES O=C1N=C(N)SC1

Description

2-Aminothiazol-4(5H)-one features a fused thiazole-imidazolone scaffold with a primary amine and carbonyl at the 2- and 4-positions, respectively. This electron-rich heterocycle exhibits enhanced solubility in polar solvents and stability under standard bench conditions. The molecule integrates readily into medicinal chemistry libraries due to its hydrogen-bonding capacity and metabolic robustness.

Application

2-Aminothiazol-4(5H)-one serves as a versatile scaffold for medicinal chemistry and heterocyclic synthesis, enabling efficient access to thiazole-based bioactive molecules. Its amine and carbonyl functionalities support diverse transformations, including amidation, alkylation, and coupling reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative library synthesis and scale-up in process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.45
  • LogP   -0.4255
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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