Lot numbers can be found on the outside label of a product:
2-Fluorobenzene-1,4-diol
-
CAS No. 55660-73-6
- Cat. No. CS-0157044
- Purity≥98%
- MDL No.MFCD00061106
*For research and further manufacturing use only, not for direct human use.
Structure of 55660-73-6
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 55660-73-6
- Cat. No. CS-0157044
- Purity ≥98%
- MDL No. MFCD00061106
- Storage 4°C, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₆H₅FO₂
- Molecular Weight 128.10
- Synonym(s) 1,4-Benzenediol, 2-fluoro-
- SMILES C1=CC(=C(C=C1O)F)O
Description
2-Fluorobenzene-1,4-diol features a fluorine substituent at the ortho position relative to one hydroxyl group, enhancing electronic effects while maintaining solubility in polar solvents. This arrangement enables direct participation in electrophilic substitution and cross-coupling reactions without requiring protection of phenolic functionalities. The compound demonstrates stability under standard bench conditions and serves as a key intermediate for bioactive heterocycles and functional materials.
Application
2-Fluorobenzene-1,4-diol serves as a valuable building block for bioactive heterocycles and pharmaceutical intermediates, offering orthogonal reactivity due to its strategically positioned fluorine and hydroxyl groups. The molecule exhibits good bench stability and facilitates selective functionalization in late-stage derivatization, enabling efficient access to substituted benzene scaffolds via standard coupling and oxidation protocols.
Synthesis
-
Route1
-
In-stock
367-12-4 - ~50%
-
In-stock
55660-73-6
References
-
Chen, Wenbin; Park, Sook Kyung; Yu, Weiping; Xiong, Ailian; Sanders, Bob G.; Kline, Kimberly European Journal of Medicinal Chemistry, 2012 , vol. 58, p. 72 - 83
-
-
Route2
-
In-stock
405-05-0 - ~91%
-
In-stock
55660-73-6
References
-
Moonen, Marielle J. H.; Westphal, Adrie H.; Rietjens, Ivonne M. C. M.; Van Berkel, Willem J. H. Advanced Synthesis and Catalysis, 2005 , vol. 347, # 7-8 p. 1027 - 1034
-
-
Route3
-
In-stock
348-27-6 - ~86%
-
In-stock
55660-73-6
References
-
Moonen, Marielle J. H.; Westphal, Adrie H.; Rietjens, Ivonne M. C. M.; Van Berkel, Willem J. H. Advanced Synthesis and Catalysis, 2005 , vol. 347, # 7-8 p. 1027 - 1034
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 40.46
- LogP 1.2369
- H_Acceptors 2
- H_Donors 2
- Rotatable_Bonds 0
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2-Fluorobenzene-1,4-diol sigma2-Fluorobenzene-1,4-diol manufacturer2-Fluorobenzene-1,4-diol price2-Fluorobenzene-1,4-diol structure2-Fluorobenzene-1,4-diol SDSbuy 2-Fluorobenzene-1,4-diol2-Fluorobenzene-1,4-diol supplier2-Fluorobenzene-1,4-diol uses2-Fluorobenzene-1,4-diol molecular weightprice of 2-Fluorobenzene-1,4-diol2-Fluorobenzene-1,4-diol chemical name formula of 2-Fluorobenzene-1,4-diol