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CS-W001157 4
Total: USD 88.00

5-(4-Formylphenyl)nicotinicacid

  • CAS No. 566198-28-5

  • Cat. No. CS-0170950
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-(4-Formylphenyl)nicotinicacid|CS-0170950

Structure of 566198-28-5

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Description

5-(4-Formylphenyl)nicotinic acid features a conjugated system linking a formyl-functionalized phenyl ring to a nicotinic acid core, enabling efficient coupling in cross-coupling and click chemistry. This bifunctional scaffold integrates seamlessly into complex molecular architectures, offering enhanced solubility and stability under standard conditions.

Application

5-(4-Formylphenyl)nicotinic acid serves as a versatile bifunctional building block for medicinal chemistry and materials science, enabling efficient synthesis of conjugated systems via Staudinger ligation or Suzuki-Miyaura coupling. The pendant aldehyde and carboxylic acid groups offer orthogonal reactivity for modular derivatization, while the rigid heteroaromatic framework enhances metabolic stability in bioactive scaffolds. Bench-stable and readily purified by recrystallization, it functions effectively in both solution-phase and solid-phase workflows.

General Information

  • CAS No. 566198-28-5
  • Cat. No. CS-0170950
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₉NO₃
  • Molecular Weight 227.22
  • Synonym(s) 5-(4-Formylphenyl)nicotinic acid
  • SMILES C1=C(C=CC(=C1)C2=CC(=CN=C2)C(=O)O)C=O

Computational Chemistry Data

  • TPSA   67.26
  • LogP   2.2593
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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