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Structure of 5669-14-7
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This sterically hindered phenyl-substituted carboxylic acid features a bulky dimethyl group adjacent to the carbonyl, enhancing metabolic stability. It serves as a key structural motif in bioactive molecule design and integrates readily into pharmaceutical scaffolds under standard coupling conditions.
2,2-Dimethyl-3-phenylpropanoic acid serves as a valuable building block in medicinal chemistry and natural product synthesis, offering enhanced steric hindrance at the α-carbon due to its geminal dimethyl substitution. The molecule facilitates controlled functionalization and stability under standard reaction conditions, enabling efficient incorporation into complex scaffolds. Its benzylic carboxylic acid functionality supports direct derivatization via esterification, amidation, or decarboxylation protocols, while maintaining compatibility with diverse protecting group strategies and orthogonal transformations in multistep syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: