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Structure of 54811-38-0
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5-Iodo-2-methylbenzoic acid features a sterically hindered aromatic core with complementary electron-withdrawing iodine and electron-donating methyl groups, enabling selective cross-coupling reactions. This bench-stable derivative delivers high functional group tolerance in palladium-catalyzed transformations.
5-Iodo-2-methylbenzoic acid serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. The iodide group facilitates efficient functionalization, while the carboxylic acid and methyl substituents offer orthogonal reactivity for further derivatization. Its bench-stable nature and compatibility with standard purification methods make it well-suited for use in medicinal chemistry and API intermediate synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: