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Structure of 5734-68-9
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4,6-Dichloro-N,N-dimethylpyrimidin-2-amine features a pyrimidine core bearing two chlorine substituents at the 4 and 6 positions and a dimethylamino group at C2. This electron-deficient heterocycle serves as a potent electrophilic coupling partner in nucleophilic substitution reactions. The molecule exhibits excellent stability under standard conditions and facilitates efficient functionalization in synthetic workflows involving amine or thiol nucleophiles.
4,6-Dichloro-N,N-dimethylpyrimidin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of substituted pyrimidine scaffolds. Its dual chlorine substituents facilitate nucleophilic aromatic substitution under mild conditions, while the dimethylamino group enhances solubility and reactivity. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis and functional group interconversions in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: