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CS-W001157 4
Total: USD 88.00

(S)-2-Fluoropropanoic acid

  • CAS No. 57965-29-4

  • Cat. No. CS-0436042
  • Purity≥95%
  • MDL No.None
  • HazMat Fee +

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    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(S)-2-Fluoropropanoic acid|CS-0436042

Structure of 57965-29-4

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Description

(S)-2-Fluoropropanoic acid is a chiral fluorinated aliphatic carboxylic acid featuring a stereogenic center at the C2 position. This configuration imparts distinct reactivity and recognition properties in asymmetric synthesis, particularly in the construction of fluorinated building blocks for medicinal chemistry. The molecule exhibits enhanced metabolic stability compared to its non-fluorinated analogs, making it valuable for bioactive compound design. Its bench-stable nature facilitates handling under standard laboratory conditions.

Application

(S)-2-Fluoropropanoic acid serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of fluorinated bioactive molecules through established enantioselective transformations. Its stability under standard reaction conditions and compatibility with common functional groups facilitate efficient incorporation into complex scaffolds. The molecule functions as a key intermediate in the construction of fluorinated analogs for drug discovery, particularly in optimizing metabolic stability and membrane permeability.

General Information

  • CAS No. 57965-29-4
  • Cat. No. CS-0436042
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₅FO₂
  • Molecular Weight 92.07
  • Synonym(s) (S)-2-Fluoropropionic acid
  • SMILES OC([C@@H](F)C)=O

Computational Chemistry Data

  • TPSA   37.3
  • LogP   0.429
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H302-H314-H319
Precautionary Statements : P210-P264-P270-P280-P304+P340-P330-P370+P378-P405-P501

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