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CS-W001157 4
Total: USD 88.00

Amino-PEG4-Boc

  • CAS No. 581065-95-4

  • Cat. No. CS-0114541
  • Molecule weight321.41
  • Purity≥96%
  • MDL No.MFCD11041116

*For research and further manufacturing use only, not for direct human use.

Amino-PEG4-Boc|CS-0114541

Structure of 581065-95-4

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General Information

  • CAS No. 581065-95-4
  • Cat. No. CS-0114541
  • Purity ≥96%
  • MDL No. MFCD11041116
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₃₁NO₆
  • Molecular Weight 321.41
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCOCCOCCOCCN

Description

Hydrocortisone 21-acetate is used as a stabilized form of the glucocorticoid in studies on stress and homeostasis.

Application

Amino-PEG4-Boc serves as a versatile bifunctional building block for peptide and polymer synthesis, enabling site-specific conjugation via its terminal amine and orthogonal Boc protection. The PEG4 spacer provides enhanced solubility and flexibility, while the Boc group offers reliable deprotection under mild acidic conditions. This reagent facilitates efficient synthesis of bioconjugates, drug delivery systems, and functionalized polymers with predictable handling and high purity.

Synthesis

  • Route1
    • HO-PEG4-OH HQ|CS-1347183
      112-60-7
    • ~%
    • In-stock
      Amino-PEG4-Boc|CS-0114541
      581065-95-4

    References

    • AMBRX, INC.; MIAO, Zhenwei; ATKINSON, Kyle, C.; BIROC, Sandra; BUSS, Timothy; COOK, Melissa; KRAYNOV, Vadim; MARSDEN, Robin; PINKSTAFF, Jason; SKIDMORE, Lillian; SUN, Ying; SZYDLIK, Angieszka; VALENTA, Ianina Patent: WO2012/166560 A1, 2012 ; WO 2012/166560 A1
  • Route2
    • null|null
      1663-39-4
    • ~%
    • In-stock
      Amino-PEG4-Boc|CS-0114541
      581065-95-4

    References

    • AMBRX, INC.; MIAO, Zhenwei; ATKINSON, Kyle, C.; BIROC, Sandra; BUSS, Timothy; COOK, Melissa; KRAYNOV, Vadim; MARSDEN, Robin; PINKSTAFF, Jason; SKIDMORE, Lillian; SUN, Ying; SZYDLIK, Angieszka; VALENTA, Ianina Patent: WO2012/166560 A1, 2012 ; WO 2012/166560 A1
  • Route3

    References

    • AMBRX, INC.; MIAO, Zhenwei; ATKINSON, Kyle, C.; BIROC, Sandra; BUSS, Timothy; COOK, Melissa; KRAYNOV, Vadim; MARSDEN, Robin; PINKSTAFF, Jason; SKIDMORE, Lillian; SUN, Ying; SZYDLIK, Angieszka; VALENTA, Ianina Patent: WO2012/166560 A1, 2012 ; WO 2012/166560 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   89.24
  • LogP   0.7433
  • H_Acceptors   7
  • H_Donors   1
  • Rotatable_Bonds   14

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