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Structure of 582300-11-6
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This tetrahydrodioxaphosphepin derivative features a sterically hindered, bench-stable phosphorus heterocycle with dual phenyl and dimethyl substitution. It integrates a piperidine moiety that enhances solubility and reactivity in synthetic transformations. The fused dioxolane-dioxaphosphole core delivers high functional group tolerance and stability under standard conditions.
1-[(3aS,8aS)-Tetrahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]piperidine serves as a stable, bench-ready phosphine building block for the synthesis of chiral ligands and catalysts. Its rigid, sterically shielded structure enhances enantioselectivity in transition-metal-catalyzed cross-coupling reactions. The molecule exhibits excellent functional group tolerance and facilitates efficient Pd-catalyzed transformations under mild conditions, making it valuable for complex molecule assembly in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: