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Structure of 58458-11-0
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2-Amino-6-(trifluoromethyl)benzonitrile features a strategically positioned trifluoromethyl group enhancing electron-withdrawal and metabolic stability, while the amino and nitrile functionalities enable direct incorporation into pharmaceutical scaffolds. This bench-stable, moisture-tolerant compound facilitates efficient synthesis of bioactive heterocycles and functionalized aryl derivatives under standard conditions.
2-Amino-6-(trifluoromethyl)benzonitrile serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds via cyclization reactions. Its amino and nitrile groups offer orthogonal reactivity for sequential functionalization, while the trifluoromethyl group enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and is compatible with standard coupling protocols, facilitating efficient access to complex intermediates in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: