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CS-W001157 4
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1-Butanol, 2-amino-, (-)- (7CI); 1-Butanol, 2-amino-, (R)-

  • CAS No. 5856-63-3

  • Cat. No. CS-W020734
  • Purity≥98%
  • MDL No.MFCD00064419

*For research and further manufacturing use only, not for direct human use.

1-Butanol, 2-amino-, (-)- (7CI); 1-Butanol, 2-amino-, (R)-|CS-W020734

Structure of 5856-63-3

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General Information

  • CAS No. 5856-63-3
  • Cat. No. CS-W020734
  • Purity ≥98%
  • MDL No. MFCD00064419
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₁NO
  • Molecular Weight 89.14
  • Synonym(s) 1-Butanol, 2-amino-, (R)-(-)- (8CI); 1-Butanol, 2-amino-, l- (4CI); R(-)-2-Amino-1-Butanol
  • SMILES CC[C@@H](N)CO

Description

(R)-2-Aminobutan-1-ol is a chiral building block featuring a primary amine and hydroxyl group on adjacent carbons, enabling direct incorporation into bioactive molecules. This stereodefined scaffold supports efficient synthesis of pharmaceutical intermediates and asymmetric catalysts under standard conditions.

Application

(R)-2-Aminobutan-1-ol serves as a valuable chiral building block in synthetic organic chemistry, enabling the construction of bioactive molecules through established amine functionalization and coupling strategies. Its bench-stable nature and well-documented stereochemical integrity facilitate reliable incorporation into peptidomimetics, pharmaceutical intermediates, and asymmetric synthesis workflows. Functions effectively in standard protection-deprotection sequences and supports diverse downstream transformations with high fidelity.

Synthesis

  • Route1

    References

    • Periasamy, Mariappan; Sivakumar, Sangarappan; Reddy, Meda Narsi Synthesis, 2003 , # 13 p. 1965 - 1967
  • Route2
    • null|null
      107-83-5
    • ~62%
    • In-stock
      1-Butanol, 2-amino-, (-)- (7CI); 1-Butanol, 2-amino-, (R)-|CS-W020734
      5856-63-3

    References

    • Esswein, Angelika; Kling, Lothar; Leser, Ulrike; Friebe, Walter-Gunar Patent: US6444832 B1, 2002 ;
  • Route3

    References

    • WO2010/148191 A2, ; Page/Page column 45-49; 59 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   -0.284
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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