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Structure of 58803-74-0
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4-Chloro-2-(methylthio)quinazoline features a chlorinated quinazoline core with a methylthio group at the 2-position, delivering enhanced electron-withdrawing character and improved metabolic stability. This scaffold integrates readily into kinase inhibitor architectures and serves as a key building block in medicinal chemistry campaigns targeting purine analogs and heterocyclic drug candidates.
4-Chloro-2-(methylthio)quinazoline serves as a versatile building block in medicinal chemistry, enabling efficient construction of quinazoline-based scaffolds. The chloro group at the 4-position facilitates nucleophilic substitution reactions, while the methylthio substituent offers moderate stability and compatibility with standard synthetic transformations. Its bench-stable nature and predictable reactivity make it well-suited for use in coupling reactions, heterocycle functionalization, and the development of kinase inhibitors and other bioactive compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: