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CS-W001157 4
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4-Chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid

  • CAS No. 59060-16-1

  • Cat. No. CS-0057312
  • Molecule weight225.63
  • Purity≥98%
  • MDL No.MFCD07367968

*For research and further manufacturing use only, not for direct human use.

4-Chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid|CS-0057312

Structure of 59060-16-1

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General Information

  • CAS No. 59060-16-1
  • Cat. No. CS-0057312
  • Purity ≥98%
  • MDL No. MFCD07367968
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈ClN₃O₂
  • Molecular Weight 225.63
  • Synonym(s) 4-chloro-1-ethylpyrazolo[3,4-b]pyridine-5-carboxylicaci
  • SMILES CCN1C2=NC=C(C(=C2C=N1)Cl)C(=O)O

Synthesis

  • Route1
    • Ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate|CS-0049469
      30720-25-3
    • ~%
    • 4-Chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid|CS-0057312
      59060-16-1

    References

    • GLAXO GROUP LIMITED Patent: WO2005/90353 A1, 2005 ; Location in patent: Page/Page column 81-82 ; WO 2005/090353 A1
  • Route2
    • null|null
      26823-99-4
    • ~%
    • 4-Chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid|CS-0057312
      59060-16-1

    References

    • Jablonski, Philippe; Nettekoven, Matthias; Patiny-Adam, Angëlique; Ratni, Hasane; Stadler, Heinz Patent: US2011/257402 A1, 2011 ; US 20110257402 A1
  • Route3

    References

    • Jablonski, Philippe; Nettekoven, Matthias; Patiny-Adam, Angëlique; Ratni, Hasane; Stadler, Heinz Patent: US2011/257402 A1, 2011 ; US 20110257402 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   68.01
  • LogP   1.8028
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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