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Structure of 5975-12-2
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2,4-Dichloro-3-nitropyridine features a pyridine core bearing two chlorine substituents at the 2- and 4-positions and a nitro group at the 3-position. This electron-deficient heterocycle serves as a pivotal scaffold for constructing complex nitrogen-containing architectures. The strategic placement of halogen and nitro groups enables selective cross-coupling and nucleophilic substitution reactions under mild conditions. Its bench-stable nature and compatibility with diverse catalytic systems make it a reliable building block in medicinal chemistry and materials synthesis.
2,4-Dichloro-3-nitropyridine serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted pyridine scaffolds via palladium-catalyzed cross-coupling and nucleophilic aromatic substitution. Its dual chloro groups exhibit orthogonal reactivity, facilitating sequential functionalization. The nitro group enhances electrophilicity at C3, promoting regioselective transformations under mild conditions. Bench-stable and readily purified by recrystallization, it functions effectively in the construction of advanced intermediates for pharmaceutical and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: