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9H-Fluoren-9-amine hydrochloride

  • CAS No. 5978-75-6

  • Cat. No. CS-0042078
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD00012536

*For research and further manufacturing use only, not for direct human use.

9H-Fluoren-9-amine hydrochloride|CS-0042078

Structure of 5978-75-6

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General Information

  • CAS No. 5978-75-6
  • Cat. No. CS-0042078
  • Purity ≥97%
  • MDL No. MFCD00012536
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₂ClN
  • Molecular Weight None
  • Synonym(s) 9H-fluoren-9-aminium
  • SMILES NC1C2=C(C3=C1C=CC=C3)C=CC=C2.[H]Cl

Description

9H-Fluoren-9-amine hydrochloride offers a stable, moisture-tolerant platform for constructing advanced organic architectures. The amine functionality integrates readily into coupling reactions, while the rigid fluorene core provides structural integrity and enhanced solubility in polar solvents. This compound serves as a key building block in materials science and pharmaceutical synthesis.

Application

9H-Fluoren-9-amine hydrochloride serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of fluorene-based scaffolds. Its amine functionality facilitates direct coupling reactions, amidation, and electrophilic substitution, while the hydrochloride salt ensures enhanced bench stability and ease of handling. Widely employed in medicinal chemistry and materials science, it functions as a key intermediate for heterocyclic systems and functionalized arylamines.

Synthesis

  • Route1

    References

    • EP2511283 A1, ; Page/Page column 92-93 ;

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P301+P310-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   3.1369
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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