Boc-Met(O2)-OH

Name: Boc-Met(O2)-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 60280-45-7
Cat. No. CS-0187742
Purity≥95%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

Boc-Met(O2)-OH is a bench-stable, moisture-tolerant amino acid derivative featuring a protected methionine side chain with a labile O₂-protected sulfide. This orthogonal protection scheme enables selective deprotection during peptide synthesis workflows. The Boc group facilitates efficient coupling under standard conditions, while the O₂-protected moiety resists premature oxidation. Ideal for incorporating oxidatively sensitive methionine residues into complex sequences.

Application

Boc-Met(O2)-OH serves as a protected methionine building block for peptide synthesis, offering stable incorporation of the methionine side chain with orthogonal protection. The Boc group enables mild deprotection under acidic conditions, while the O₂-protected sulfide maintains integrity during coupling steps. Its compatibility with standard Fmoc and Boc strategies facilitates efficient sequence assembly, and the functional group tolerance supports diverse synthetic workflows in medicinal chemistry and API development.

General Information

CAS No. 60280-45-7
Cat. No. CS-0187742
Purity ≥95%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₉NO₆S
Molecular Weight 281.33
Synonym(s) Boc-L-methionine sulfone
SMILES CC(C)(OC(N[C@H](C(O)=O)CCS(=O)(C)=O)=O)C

Computational Chemistry Data

TPSA 109.77
LogP 0.399
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 5

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Other Classifications

Building Blocks Functional Group Sulfone

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Fatty chain compounds

Life Science Amino Acids and their Derivatives Methionine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

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Boc-Met(O2)-OH

CAS No. 60280-45-7

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