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CS-W001157 4
Total: USD 88.00

3-Fluoro-5-methoxyphenylboronic acid

  • CAS No. 609807-25-2

  • Cat. No. CS-W000953
  • Purity≥95%
  • MDL No.MFCD07363780

*For research and further manufacturing use only, not for direct human use.

3-Fluoro-5-methoxyphenylboronic acid|CS-W000953

Structure of 609807-25-2

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General Information

  • CAS No. 609807-25-2
  • Cat. No. CS-W000953
  • Purity ≥95%
  • MDL No. MFCD07363780
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈BFO₃
  • Molecular Weight 169.95
  • Synonym(s) Boronic acid, B-(3-fluoro-5-methoxyphenyl)-
  • SMILES COc1cc(F)cc(c1)B(O)O

Description

3-Fluoro-5-methoxyphenylboronic acid features a boronate moiety flanked by electron-withdrawing fluorine and electron-donating methoxy groups, enabling selective Suzuki-Miyaura coupling under mild conditions. This bench-stable reagent integrates seamlessly into complex molecule synthesis, offering high functional group tolerance and reliable yield in C–C bond formation.

Application

3-Fluoro-5-methoxyphenylboronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. Its ortho-fluoro and meta-methoxy substituents provide enhanced stability and predictable reactivity, while the boronic acid functionality offers excellent bench stability and compatibility with diverse functional groups. This compound facilitates the construction of substituted biaryl scaffolds commonly found in pharmaceutical intermediates and agrochemicals.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   -0.4859
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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