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CS-W001157 4
Total: USD 88.00

5-Chloro-2-nitrophenol

  • CAS No. 611-07-4

  • Cat. No. CS-W003599
  • Purity≥98%
  • MDL No.MFCD09260849
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Chloro-2-nitrophenol|CS-W003599

Structure of 611-07-4

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Description

5-Chloro-2-nitrophenol is a chlorinated nitrophenol featuring a nitro group at the ortho position relative to the hydroxyl, enhancing electrophilic reactivity. This electron-deficient aromatic system facilitates efficient coupling in cross-coupling and cyclization reactions. The compound exhibits bench-stable handling with good solubility in common organic solvents, enabling straightforward integration into synthetic sequences for pharmaceutical intermediates and specialty dyes.

Application

5-Chloro-2-nitrophenol serves as a versatile building block in synthetic organic chemistry, enabling direct access to substituted heterocycles and pharmaceutical intermediates. Its ortho-nitro and para-chloro functionalities provide orthogonal reactivity for sequential transformations, including nucleophilic aromatic substitution and catalytic coupling reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in medicinal chemistry and process development workflows.

General Information

  • CAS No. 611-07-4
  • Cat. No. CS-W003599
  • Purity ≥98%
  • MDL No. MFCD09260849
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄ClNO₃
  • Molecular Weight 173.55
  • Synonym(s) Phenol, 5-chloro-2-nitro-
  • SMILES OC1=CC(Cl)=CC=C1[N+]([O-])=O

Computational Chemistry Data

  • TPSA   63.37
  • LogP   1.9538
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H317-H318-H410
Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P501

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