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Structure of 611-07-4
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5-Chloro-2-nitrophenol is a chlorinated nitrophenol featuring a nitro group at the ortho position relative to the hydroxyl, enhancing electrophilic reactivity. This electron-deficient aromatic system facilitates efficient coupling in cross-coupling and cyclization reactions. The compound exhibits bench-stable handling with good solubility in common organic solvents, enabling straightforward integration into synthetic sequences for pharmaceutical intermediates and specialty dyes.
5-Chloro-2-nitrophenol serves as a versatile building block in synthetic organic chemistry, enabling direct access to substituted heterocycles and pharmaceutical intermediates. Its ortho-nitro and para-chloro functionalities provide orthogonal reactivity for sequential transformations, including nucleophilic aromatic substitution and catalytic coupling reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in medicinal chemistry and process development workflows.
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GHS No : GHS05,GHS07,GHS09
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Signal Word : Danger
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H317-H318-H410
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Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P501
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Lot numbers can be found on the outside label of a product: