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CS-W001157 4
Total: USD 88.00

1-Methyl-4-(trifluoromethyl)benzene

  • CAS No. 6140-17-6

  • Cat. No. CS-W017941
  • Purity≥98%
  • MDL No.MFCD00075476

*For research and further manufacturing use only, not for direct human use.

1-Methyl-4-(trifluoromethyl)benzene|CS-W017941

Structure of 6140-17-6

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General Information

  • CAS No. 6140-17-6
  • Cat. No. CS-W017941
  • Purity ≥98%
  • MDL No. MFCD00075476
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇F₃
  • Molecular Weight 160.14
  • Synonym(s) α,α,α-trifluoro-p-xylene
  • SMILES FC(C1=CC=C(C)C=C1)(F)F

Description

1-Methyl-4-(trifluoromethyl)benzene features a trifluoromethyl group that imparts strong electron-withdrawing character and enhanced metabolic stability. This aromatic compound serves as a valuable building block in pharmaceutical synthesis, where its hydrophobic and sterically defined structure supports targeted molecular design.

Application

1-Methyl-4-(trifluoromethyl)benzene serves as a valuable aryl building block in medicinal chemistry and materials science, offering enhanced lipophilicity and metabolic stability due to the electron-withdrawing trifluoromethyl group. Its bench-stable nature and compatibility with standard cross-coupling reactions enable efficient incorporation into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.01382
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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