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Structure of 615-41-8
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1-Chloro-2-iodobenzene is a halogenated aromatic compound featuring ortho-chloro and iodine substituents on the benzene ring. This configuration enables efficient cross-coupling reactions in palladium-catalyzed transformations, offering high reactivity and predictable regiochemistry. The molecule exhibits enhanced stability under standard bench conditions and integrates readily into complex synthetic sequences for pharmaceutical and agrochemical intermediates.
1-Chloro-2-iodobenzene serves as a versatile biaryl coupling precursor in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki, Stille, and Negishi conditions. The ortho-halogen substitution pattern provides predictable reactivity and facilitates selective functionalization. Bench-stable and readily purified by distillation, it functions reliably in multi-step synthesis of pharmaceutical intermediates and advanced heterocyclic scaffolds.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: