Lot numbers can be found on the outside label of a product:
3-Amino-1-benzofuran-2-carbonitrile
-
CAS No. 62208-67-7
- Cat. No. CS-0060570
- Purity≥95%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 62208-67-7
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 62208-67-7
- Cat. No. CS-0060570
- Purity ≥95%
- MDL No. None
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₆N₂O
- Molecular Weight 158.16
- Synonym(s) 3-Amino-benzofuran-2-carbonitrile
- SMILES C1=CC=C2C(=C1)C(=C(C#N)O2)N
Description
3-Amino-1-benzofuran-2-carbonitrile features a fused benzofuran scaffold bearing an electron-rich amino group and a reactive nitrile moiety. This combination enables direct incorporation into heterocyclic architectures, facilitating rapid access to bioactive scaffolds in medicinal chemistry. The compound exhibits excellent stability under standard bench conditions and demonstrates favorable solubility in common organic solvents for synthetic manipulation.
Application
3-Amino-1-benzofuran-2-carbonitrile serves as a versatile building block for heterocyclic synthesis, enabling efficient access to fused polycyclic scaffolds via C–H functionalization and palladium-catalyzed coupling reactions. The amino and nitrile groups offer orthogonal reactivity, facilitating derivatization through amidation, cyclization, or electrophilic substitution. Bench-stable and readily purified by recrystallization, it functions effectively in medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.
Synthesis
-
Route1
-
49615-99-8 - ~64%
-
In-stock
62208-67-7
References
-
Ando, Kumiko; Tsuji, Eriko; Ando, Yuko; Kuwata, Noriko; Kunitomo, Jun-Ichi; Yamashita, Masayuki; Ohta, Shunsaku; Kohno, Shigekatsu; Ohishi, Yoshitaka Organic and Biomolecular Chemistry, 2004 , vol. 2, # 4 p. 625 - 635
-
-
Route2
-
In-stock
611-20-1 -
107-14-2 - ~0%
-
In-stock
62208-67-7
-
49615-99-8
References
-
Ando, Kumiko; Tsuji, Eriko; Ando, Yuko; Kuwata, Noriko; Kunitomo, Jun-Ichi; Yamashita, Masayuki; Ohta, Shunsaku; Kohno, Shigekatsu; Ohishi, Yoshitaka Organic and Biomolecular Chemistry, 2004 , vol. 2, # 4 p. 625 - 635
-
-
Route3
-
In-stock
611-20-1
-
590-17-0
- ~61%
-
In-stock
62208-67-7
References
-
Loidreau, Yvonnick; Dubouilh-Benard, Carole; Marchand, Pascal; Nourrisson, Marie-Renee; Duflos, Muriel; Buquet, Catherine; Corbiere, Cecile; Besson, Thierry Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 5 p. 1187 - 1197
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 62.95
- LogP 1.88668
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 0
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 3-Amino-1-benzofuran-2-carbonitrile sigma3-Amino-1-benzofuran-2-carbonitrile manufacturer3-Amino-1-benzofuran-2-carbonitrile price3-Amino-1-benzofuran-2-carbonitrile structure3-Amino-1-benzofuran-2-carbonitrile SDSbuy 3-Amino-1-benzofuran-2-carbonitrile3-Amino-1-benzofuran-2-carbonitrile supplier3-Amino-1-benzofuran-2-carbonitrile uses3-Amino-1-benzofuran-2-carbonitrile molecular weightprice of 3-Amino-1-benzofuran-2-carbonitrile3-Amino-1-benzofuran-2-carbonitrile chemical name formula of 3-Amino-1-benzofuran-2-carbonitrile