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CS-W001157 4
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{4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-2-yl}methanol

  • CAS No. 623565-69-5

  • Cat. No. CS-W000017
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

{4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-2-yl}methanol|CS-W000017

Structure of 623565-69-5

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General Information

  • CAS No. 623565-69-5
  • Cat. No. CS-W000017
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁N₃O
  • Molecular Weight 153.18
  • Synonym(s) (4,5,6,7-Tetrahydropyrazolo[1,5-A]pyrazin-2-YL)methanol
  • SMILES OCc1nn2c(c1)CNCC2

Description

This pyrazolo[1,5-a]pyrazine derivative features a reactive benzylic alcohol moiety enabling direct functionalization in synthetic workflows. The fused heterocyclic core imparts enhanced stability and tailored electronic properties, facilitating integration into advanced pharmaceutical intermediates and bioactive molecule scaffolds under standard conditions.

Application

{4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-2-yl}methanol serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyrazolo[1,5-a]pyrazine derivatives. Its primary alcohol functionality facilitates straightforward derivatization via esterification, etherification, or oxidation to the corresponding aldehyde. The scaffold exhibits excellent bench stability and compatibility with standard purification methods, making it well-suited for medicinal chemistry campaigns and process development in API discovery.

Synthesis

  • Route1
    • null|null
      623565-16-2
    • ~96%
    • In-stock
      {4H,5H,6H,7H-pyrazolo[1,5-a]pyrazin-2-yl}methanol|CS-W000017
      623565-69-5

    References

    • Wyeth Patent: US2006/276445 A1, 2006 ; Location in patent: Page/Page column 43 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   50.08
  • LogP   -0.5214
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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