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Structure of 62484-29-1
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2,4,8-Trichloroquinazoline features a highly electron-deficient quinazoline core with three strategically positioned chlorine substituents. This configuration enhances its reactivity in nucleophilic substitution processes and provides stability under standard bench conditions. The molecule serves as a robust scaffold for constructing complex heterocyclic systems in medicinal chemistry and materials science applications.
2,4,8-Trichloroquinazoline serves as a versatile building block in medicinal chemistry, enabling direct functionalization at multiple positions due to its electron-deficient core. The trichloro substitution pattern facilitates nucleophilic aromatic substitution with broad functional group tolerance, supporting efficient synthesis of quinazoline-based scaffolds. Its bench-stable solid form and compatibility with standard coupling protocols make it ideal for high-throughput library generation and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: