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CS-W001157 4
Total: USD 88.00

Ethoxyacetic acid

  • CAS No. 627-03-2

  • Cat. No. CS-0071579
  • Purity≥96%
  • MDL No.MFCD00004310

*For research and further manufacturing use only, not for direct human use.

Ethoxyacetic acid|CS-0071579

Structure of 627-03-2

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General Information

  • CAS No. 627-03-2
  • Cat. No. CS-0071579
  • Purity ≥96%
  • MDL No. MFCD00004310
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈O₃
  • Molecular Weight None
  • Synonym(s) None
  • SMILES O=C(O)COCC

Description

Ethoxyacetic acid features a polar ethoxy group adjacent to a carboxylic acid, enhancing solubility in aqueous and organic solvents. This functional group arrangement supports its use in synthesizing ester intermediates and bioactive molecules, particularly where controlled hydrolysis or metabolic stability is required.

Application

Ethoxyacetic acid serves as a versatile building block in synthetic organic chemistry, enabling efficient access to ester-functionalized intermediates and bioactive scaffolds. Its dual functionality—carboxylic acid and ethoxy group—facilitates straightforward derivatization, including amidation, esterification, and cyclization reactions. The compound exhibits good bench stability and is readily purified by distillation or recrystallization, supporting its use in scalable synthesis and process development workflows.

Synthesis

  • Route1

    References

    • Annales de Chimie (Cachan, France), , vol. <8>16, p. 318
  • Route2
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      22056-82-2
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    • In-stock
      Ethoxyacetic acid|CS-0071579
      627-03-2

    References

    • Journal of the Chemical Society, , p. 2950
  • Route3
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      630-20-6
    • ~%
    • In-stock
      Ethoxyacetic acid|CS-0071579
      627-03-2

    References

    • Journal fuer Praktische Chemie (Leipzig), , vol. <2>7, p. 113,115

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   0.1075
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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