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Structure of 6310-19-6
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4-(tert-Butyl)-2-nitroaniline features a sterically hindered tert-butyl group flanking a nitro-substituted aromatic ring, enhancing stability and solubility in organic media. This electron-deficient aniline derivative integrates readily into coupling reactions and serves as a key intermediate for pharmaceuticals and agrochemicals.
4-(tert-Butyl)-2-nitroaniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted anilines via selective reduction. Its tert-butyl group provides steric protection and enhanced solubility, while the ortho-nitro functionality facilitates electrophilic substitution and subsequent coupling reactions. The compound exhibits excellent bench stability and simplifies purification due to low volatility and high crystallinity, making it well-suited for multi-step syntheses and scale-up processes.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅱ
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: