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CS-W001157 4
Total: USD 88.00

2-Cyano-N-methyl-acetamide

  • CAS No. 6330-25-2

  • Cat. No. CS-W018827
  • Purity≥97%
  • MDL No.MFCD00090119

*For research and further manufacturing use only, not for direct human use.

2-Cyano-N-methyl-acetamide|CS-W018827

Structure of 6330-25-2

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General Information

  • CAS No. 6330-25-2
  • Cat. No. CS-W018827
  • Purity ≥97%
  • MDL No. MFCD00090119
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆N₂O
  • Molecular Weight 98.10
  • Synonym(s) N-methyl Cyano Acetamide
  • SMILES C(C(NC)=O)C#N

Description

2-Cyano-N-methyl-acetamide features a nitrile group flanked by an amide moiety, delivering high stability and compatibility with diverse synthetic transformations. This bifunctional scaffold integrates seamlessly into heterocyclic systems and serves as a key intermediate in the development of bioactive compounds.

Application

2-Cyano-N-methyl-acetamide serves as a versatile building block in synthetic organic chemistry, enabling efficient access to heterocyclic scaffolds via cyclization reactions. Its nitrile and amide functionalities offer orthogonal reactivity, facilitating transformations under mild conditions. The molecule exhibits excellent bench stability and is compatible with a range of functional groups, making it well-suited for use in medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • null|null
      105-56-6
    • null|null
      74-89-5
    • ~97%
    • In-stock
      2-Cyano-N-methyl-acetamide|CS-W018827
      6330-25-2

    References

    • SANOFI-AVENTIS Patent: US2011/251194 A1, 2011 ; Location in patent: Page/Page column 14 ;
  • Route2
    • null|null
      372-09-8
    • null|null
      74-89-5
    • ~87%
    • In-stock
      2-Cyano-N-methyl-acetamide|CS-W018827
      6330-25-2

    References

    • SANOFI-AVENTIS Patent: US2010/144757 A1, 2010 ; Location in patent: Page/Page column 6; 7 ;
  • Route3

    References

    • Helvetica Chimica Acta, , vol. 81, # 7 p. 1319 - 1328

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.89
  • LogP   -0.35392
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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