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Structure of 6336-68-1
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4-(1-Piperidinylsulfonyl)benzenamine features a sulfonamide-linked piperidine ring that enhances solubility and metabolic stability. This electron-deficient aryl scaffold integrates readily into pharmaceutical intermediates, offering robust reactivity under standard coupling conditions. The para-substituted aniline moiety enables direct functionalization in late-stage derivatization.
4-(1-Piperidinylsulfonyl)benzenamine serves as a versatile building block in medicinal chemistry, enabling the construction of sulfonamide-containing scaffolds through standard coupling reactions. Its piperidine-sulfonamide motif offers enhanced solubility and metabolic stability, while the aniline functionality facilitates further derivatization via electrophilic substitution or transition-metal-catalyzed cross-coupling. The compound exhibits excellent bench stability and is readily purified by recrystallization or chromatography, making it well-suited for high-throughput synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: