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Structure of 64085-52-5
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5-Bromo-2-iodoaniline delivers a dual halogenated aniline scaffold with orthogonal reactivity, enabling sequential cross-coupling strategies in complex molecule assembly. The para-bromo and ortho-iodo substituents facilitate selective Pd-catalyzed transformations under standard conditions, while the amine group provides a handle for derivatization. This compound exhibits bench-stable behavior and moisture-tolerant handling characteristics, simplifying integration into multi-step synthetic sequences.
5-Bromo-2-iodoaniline serves as a versatile diarylated aniline building block for cross-coupling reactions and heterocycle synthesis. Its orthogonal halogen reactivity enables sequential functionalization, with the bromo group typically participating in palladium-catalyzed couplings while the iodo substituent offers high reactivity in Suzuki or Sonogashira transformations. The compound exhibits good bench stability and is readily purified by recrystallization, facilitating integration into multi-step synthetic sequences for pharmaceutical and agrochemical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: