Boc-N-Me-Tyr(Bzl)-OH

Name: Boc-N-Me-Tyr(Bzl)-OH
Brand: ChemScene
Availability: InStock
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CAS No. 64263-81-6
Cat. No. CS-W011749
Purity≥98%
MDL No.MFCD00038755

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Description

Boc-N-Me-Tyr(Bzl)-OH is a protected tyrosine derivative featuring a tert-butoxycarbonyl group on the amine and a benzyl ether on the phenolic hydroxyl. This dual protection enables stable incorporation into peptide synthesis workflows, where the Boc group facilitates orthogonal deprotection. The benzyl-protected hydroxyl resists premature oxidation, enhancing handling reliability in complex sequences.

Application

Boc-N-Me-Tyr(Bzl)-OH serves as a versatile building block for peptide synthesis, enabling the incorporation of N-methylated tyrosine residues with orthogonal protection. The Boc group provides stable N-terminal protection, while the benzyl ether protects the phenolic hydroxyl, allowing selective deprotection and functionalization. This derivative facilitates efficient coupling reactions and is compatible with standard Fmoc-based workflows, offering robust bench stability and ease of purification in complex sequence assembly.

General Information

CAS No. 64263-81-6
Cat. No. CS-W011749
Purity ≥98%
MDL No. MFCD00038755
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₂H₂₇NO₅
Molecular Weight 385.46
Synonym(s) None
SMILES O=C(O)[C@@H](N(C(OC(C)(C)C)=O)C)CC1=CC=C(OCC2=CC=CC=C2)C=C1

Computational Chemistry Data

TPSA 76.07
LogP 4.1282
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 7

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Tyrosine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

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Boc-N-Me-Tyr(Bzl)-OH

CAS No. 64263-81-6

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