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CS-W001157 4
Total: USD 88.00

Thalidomide-5-OH

  • CAS No. 64567-60-8

  • Cat. No. CS-0044368
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD24386541

*For research and further manufacturing use only, not for direct human use.

Thalidomide-5-OH|CS-0044368

Structure of 64567-60-8

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General Information

  • CAS No. 64567-60-8
  • Cat. No. CS-0044368
  • Purity ≥97%
  • MDL No. MFCD24386541
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₀N₂O₅
  • Molecular Weight None
  • Synonym(s) 5-Hydroxythalidomide
  • SMILES O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(O)=C3)=O

Description

Thalidomide-5-OH features a hydroxyl group at the 5-position of the phthalimide ring, enhancing solubility and enabling site-specific derivatization. This modification improves metabolic stability and facilitates conjugation in targeted protein degradation strategies. The compound serves as a key intermediate for developing novel immunomodulatory agents with tailored pharmacokinetic profiles.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P317-P337+P317-P362+P364

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Computational Chemistry Data

  • TPSA   103.78
  • LogP   -0.2363
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   1

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