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Structure of 64984-08-3
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1-Iodo-4-(methylsulfonyl)benzene features a reactive iodine handle paired with a strongly electron-withdrawing methylsulfonyl group, enabling efficient cross-coupling transformations. The sulfone moiety enhances solubility and stability under standard reaction conditions, facilitating its use in Suzuki-Miyaura and Negishi couplings for constructing complex aromatic architectures.
1-Iodo-4-(methylsulfonyl)benzene serves as a versatile aryl halide coupling partner in palladium-catalyzed cross-coupling reactions. The methylsulfonyl group provides strong electron-withdrawing character and excellent functional group stability, enabling reliable Suzuki, Stille, and Negishi couplings. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for constructing biaryl scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: