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Structure of 65078-77-5
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2,3-Dichloro-6-nitroaniline features a nitro group at the para position relative to the amino functionality, creating a strongly electron-deficient aromatic system. This configuration enhances reactivity in electrophilic substitution and facilitates coupling reactions. The presence of two chlorine atoms at adjacent positions provides sites for palladium-catalyzed cross-coupling transformations. The compound exhibits bench-stable handling characteristics and serves as a key intermediate in the synthesis of advanced pharmaceuticals and agrochemicals.
2,3-Dichloro-6-nitroaniline serves as a valuable building block in heterocyclic synthesis and medicinal chemistry, offering orthogonal reactivity through its nitro group and two chloro substituents. The molecule exhibits good bench stability and facilitates direct electrophilic substitution or nucleophilic displacement reactions, enabling efficient access to substituted anilines and complex aromatic scaffolds. Its functional group tolerance supports integration into multi-step synthetic sequences for API intermediates.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: