7-Bromoquinolin-4-amine

Name: 7-Bromoquinolin-4-amine
Brand: ChemScene
Availability: InStock
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CAS No. 65340-74-1
Cat. No. CS-0312303
Purity≥97%
MDL No.MFCD06411037

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 65340-74-1

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Description

7-Bromoquinolin-4-amine integrates a bromine atom at the 7-position and an amine group at the 4-position of the quinoline scaffold, delivering a versatile building block with enhanced reactivity for cross-coupling and functionalization. This electron-deficient heterocycle features high stability under standard conditions, enabling efficient incorporation into pharmaceutical intermediates and advanced materials.

Application

7-Bromoquinolin-4-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromo and amino functionalities. The molecule exhibits excellent bench stability and facilitates efficient diversification of quinoline scaffolds through Suzuki, Stille, or Buchwald-Hartwig couplings. Its dual reactive sites allow for sequential functionalization, making it particularly valuable in the synthesis of kinase inhibitors and other heterocyclic drug candidates.

General Information

CAS No. 65340-74-1
Cat. No. CS-0312303
Purity ≥97%
MDL No. MFCD06411037
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₇BrN₂
Molecular Weight 223.07
Synonym(s) 4-quinolinamine, 7-bromo-
SMILES NC1=CC=NC2=CC(Br)=CC=C12

Computational Chemistry Data

TPSA 38.91
LogP 2.5795
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds quinoline compounds

Key Words

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7-Bromoquinolin-4-amine

CAS No. 65340-74-1

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