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Structure of 65373-52-6
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Oxazole-2-carbaldehyde delivers a reactive aldehyde handle at the 2-position of an electron-deficient oxazole ring. This configuration enables direct coupling in heterocyclic synthesis, particularly in transition-metal-catalyzed transformations and conjugate additions. The moiety integrates readily into bioactive scaffolds and functional materials due to its stability under standard conditions and compatibility with diverse reaction environments.
Oxazole-2-carbaldehyde serves as a versatile heterocyclic building block in medicinal chemistry and synthetic organic chemistry. Its aldehyde functionality enables direct incorporation into Ugi, Mannich, and reductive amination reactions, while the oxazole ring provides metabolic stability and favorable pharmacokinetic properties. The compound exhibits good bench stability and facilitates efficient derivatization under mild conditions, making it well-suited for modular synthesis of bioactive molecules and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: