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Structure of 65433-99-0
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Quinoline-6-sulfonyl chloride serves as a reactive acylating agent for amine functionalization, enabling direct installation of a quinoline-based sulfonyl group. This moiety enhances solubility and provides a rigid, electron-deficient scaffold useful in medicinal chemistry and fluorescent probe design. The reagent exhibits high stability under standard conditions and facilitates efficient coupling without requiring additional activators.
Quinoline-6-sulfonyl chloride serves as a versatile building block for the synthesis of sulfonamide-containing heterocycles, enabling efficient introduction of a sulfonyl group at the C6 position of quinoline. Its reactivity facilitates nucleophilic substitution with amines and alcohols under mild conditions, offering high functional group tolerance and ease of purification. The resulting sulfonamides are valuable intermediates in medicinal chemistry and catalytic system design.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: