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Structure of 599183-35-4
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1H-Indazole-5-sulfonyl chloride features a reactive sulfonyl chloride group positioned at the 5-position of the indazole core, enabling direct conjugation with nucleophiles. The electron-deficient aromatic system enhances electrophilicity, facilitating efficient amide and sulfonamide formation under mild conditions. This bench-stable reagent integrates readily into complex molecule synthesis, offering precise functionalization in pharmaceutical and agrochemical development workflows.
1H-Indazole-5-sulfonyl chloride serves as a versatile acylating agent for the installation of sulfonyl groups at the C5-position of indazole scaffolds. It facilitates efficient amide and sulfonamide formation under mild conditions, enabling rapid access to functionalized heterocycles relevant to medicinal chemistry. The reagent exhibits good bench stability and compatibility with common protecting groups, simplifying purification and integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2923
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Class : 8,6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H314-H331
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P330+P331-P302+P352-P304+P340-P330-P361+P364-P363-P405-P501
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Lot numbers can be found on the outside label of a product: