Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Bromo-4-fluorophenylamine

  • CAS No. 656-64-4

  • Cat. No. CS-W008702
  • Molecule weight190.01
  • Purity≥98%
  • MDL No.MFCD03788559

*For research and further manufacturing use only, not for direct human use.

3-Bromo-4-fluorophenylamine|CS-W008702

Structure of 656-64-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 656-64-4
  • Cat. No. CS-W008702
  • Purity ≥98%
  • MDL No. MFCD03788559
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrFN
  • Molecular Weight 190.01
  • Synonym(s) Aniline, 3-bromo-4-fluoro- (6CI,7CI,8CI); 3-Bromo-4-fluoroaniline; 3-Bromo-4-fluorobenzenamine; 3-Bromo-4-Fluoro Aniline
  • SMILES FC1=CC=C(N)C=C1Br

Description

N-Succinimidyl 3-(propargyloxy)propionate is an acetylene-containing reagent with NHS ester functionality for reaction with amines.

Application

3-Bromo-4-fluorophenylamine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the fluoro substituent enhances metabolic stability and modulates electronic properties. Its bench-stable solid form simplifies handling and purification, making it ideal for constructing complex heterocyclic scaffolds and API intermediates.

Synthesis

  • Route1

    References

    • 3-DIMENSIONAL PHARMACEUTICALS, INC. Patent: WO2003/99805 A1, 2003 ; Location in patent: Page 434 ;
  • Route2

    References

    • Austin, William B.; Bilow, Norman; Kelleghan, William J.; Lau, Kreisler S. Y. Journal of Organic Chemistry, 1981 , vol. 46, # 11 p. 2280 - 2286
  • Route3
    • null|null
      7758-19-2
    • In-stock
      3-Bromo-4-fluorobenzaldehyde|CS-B1308
      77771-02-9
    • ~96%
    • In-stock
      3-Bromo-4-fluorophenylamine|CS-W008702
      656-64-4

    References

    • 3-Dimensional Pharmaceuticals, Inc. Patent: US2004/9995 A1, 2004 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P311-P312-P330-P361-P363-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.1704
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Bromo-4-fluorophenylamine sigma3-Bromo-4-fluorophenylamine manufacturer3-Bromo-4-fluorophenylamine price3-Bromo-4-fluorophenylamine structure3-Bromo-4-fluorophenylamine SDSbuy 3-Bromo-4-fluorophenylamine3-Bromo-4-fluorophenylamine supplier3-Bromo-4-fluorophenylamine uses3-Bromo-4-fluorophenylamine molecular weightprice of 3-Bromo-4-fluorophenylamine3-Bromo-4-fluorophenylamine chemical name formula of 3-Bromo-4-fluorophenylamine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label