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Structure of 660845-30-7
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This difluoromethyl-substituted pyrazole aldehyde features a reactive aldehyde group flanked by electron-withdrawing chlorine and difluoromethyl moieties, enhancing electrophilicity for use in heterocyclic coupling reactions. The methyl group at the pyrazole nitrogen improves solubility and stability under standard conditions.
5-Chloro-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to heterocyclic scaffolds via standard coupling and functional group transformation protocols. The difluoromethyl group enhances metabolic stability and modulates lipophilicity, while the aldehyde functionality facilitates reductive amination, imine formation, and conjugate addition reactions. Bench-stable and compatible with diverse reaction conditions, it supports scalable synthesis of bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: