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Structure of 6640-50-2
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8-Hydroxy-1,2,3,4-tetrahydroquinoline features a fused heterocyclic scaffold with a phenolic hydroxyl group at the 8-position, enabling direct coordination to metal ions and participation in hydrogen bonding. This structural motif enhances solubility in polar solvents and supports its utility in ligand design for transition metal catalysis and as a building block in bioactive molecule synthesis.
8-Hydroxy-1,2,3,4-tetrahydroquinoline serves as a versatile heterocyclic building block in medicinal chemistry, offering a readily functionalizable scaffold for derivatization at the hydroxyl and aromatic positions. Its stability under standard reaction conditions facilitates coupling, oxidation, and substitution protocols, enabling efficient access to bioactive analogs and complex ring systems. The molecule functions as a key intermediate in the synthesis of quinoline-based pharmaceuticals and natural product derivatives.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H412
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Precautionary Statements : P264-P270-P273-P330-P501
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Lot numbers can be found on the outside label of a product: