Lot numbers can be found on the outside label of a product:
Please log in for operation!
*For research and further manufacturing use only, not for direct human use.
Structure of 66522-06-3
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
4-(tert-Butyl)-2-chloropyrimidine features a sterically hindered tert-butyl group at the 4-position, enhancing stability and solubility in organic media. The electron-deficient pyrimidine core facilitates nucleophilic substitution reactions, enabling efficient coupling with amines, thiols, and other heteroatoms under mild conditions. This reactivity profile supports its use in pharmaceutical intermediates and functional material synthesis.
4-(tert-Butyl)-2-chloropyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The chloropyrimidine moiety reacts reliably with boronic acids, amines, and thiols under standard conditions, while the tert-butyl group enhances solubility and provides steric protection during synthesis. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for constructing complex heterocyclic scaffolds in API development.
|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Lot numbers can be found on the outside label of a product: