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CS-W001157 4
Total: USD 88.00

1-(5-Hydroxypyridin-2-yl)ethanone

  • CAS No. 67310-56-9

  • Cat. No. CS-W021245
  • Purity≥98%
  • MDL No.MFCD10697710

*For research and further manufacturing use only, not for direct human use.

1-(5-Hydroxypyridin-2-yl)ethanone|CS-W021245

Structure of 67310-56-9

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General Information

  • CAS No. 67310-56-9
  • Cat. No. CS-W021245
  • Purity ≥98%
  • MDL No. MFCD10697710
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇NO₂
  • Molecular Weight 137.14
  • Synonym(s) Ethanone, 1-(5-hydroxy-2-pyridinyl)- (9CI)
  • SMILES CC(C1=NC=C(O)C=C1)=O

Description

1-(5-Hydroxypyridin-2-yl)ethanone features a pyridine ring bearing both hydroxyl and ketone functionalities at adjacent positions, enabling dual coordination sites for metal chelation. This structural motif supports integration into ligand frameworks for transition-metal catalysis and offers enhanced solubility in polar solvents compared to analogous non-hydroxylated analogs.

Application

1-(5-Hydroxypyridin-2-yl)ethanone serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyridine-based scaffolds through standard functional group transformations. Its hydroxyl and ketone functionalities offer orthogonal reactivity, facilitating coupling reactions, derivatization, and protection strategies. The compound exhibits good bench stability and is readily purified by recrystallization or chromatography, making it well-suited for medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   0.9898
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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