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Structure of 676501-85-2
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5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carbonitrile features a boronate ester group coupled with an electron-deficient thiophene core bearing a nitrile. This combination enables efficient palladium-catalyzed cross-coupling reactions under mild conditions, delivering functionalized heteroaryl architectures with high stability and predictable reactivity in synthetic workflows.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carbonitrile serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylborolane moiety enables stable, air-tolerant handling and broad functional group compatibility. It facilitates efficient construction of biaryl and heteroaryl scaffolds, particularly in the synthesis of conjugated materials and medicinally relevant thienyl derivatives.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H319
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: