(R)-2-(Aminomethyl)-1-N-Boc-piperidine

Name: (R)-2-(Aminomethyl)-1-N-Boc-piperidine
Brand: ChemScene
Availability: InStock
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CAS No. 683233-14-9
Cat. No. CS-0002012
Purity≥95%
MDL No.MFCD06659040

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-2-(Aminomethyl)-1-N-Boc-piperidine|CS-0002012

Structure of 683233-14-9

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Description

(R)-2-(Aminomethyl)-1-N-Boc-piperidine is a chiral piperidine derivative featuring a protected amine and a primary aminoalkyl side chain. This bench-stable, moisture-tolerant building block integrates readily into peptide-like scaffolds and small-molecule libraries, enabling efficient access to bioactive heterocycles through standard coupling and deprotection protocols.

Application

(R)-2-(Aminomethyl)-1-N-Boc-piperidine serves as a versatile chiral building block for the synthesis of bioactive molecules, enabling efficient access to piperidine-containing pharmaceuticals. The Boc-protected amine offers excellent stability and ease of purification, while the pendant primary amine facilitates diverse functionalization via standard coupling reactions. This scaffold is well-suited for medicinal chemistry campaigns requiring stereocontrolled construction of nitrogen-rich heterocycles.

General Information

CAS No. 683233-14-9
Cat. No. CS-0002012
Purity ≥95%
MDL No. MFCD06659040
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₂₂N₂O₂
Molecular Weight 214.30
Synonym(s) 1-Piperidinecarboxylic acid, 2-(aminomethyl)-, 1,1-dimethylethyl ester, (2R)-
SMILES O=C(OC(C)(C)C)N(CCCC1)[C@H]1CN

Computational Chemistry Data

TPSA 55.56
LogP 1.7347
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-2-(Aminomethyl)-1-N-Boc-piperidine

CAS No. 683233-14-9

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