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Structure of 685084-08-6
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2,3-Dihydro-1H-isoindole-5-carboxylic acid features a fused bicyclic core with a carboxylic acid at the 5-position, enabling direct integration into bioactive scaffolds. The planar, electron-rich aromatic system enhances π-stacking interactions in target binding, while the acidic proton supports derivatization via amide or ester formation. This structure offers enhanced solubility and stability under standard bench conditions, facilitating use in medicinal chemistry campaigns and macrocycle synthesis.
2,3-Dihydro-1H-isoindole-5-carboxylic acid serves as a versatile scaffold in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard functional group transformations. Its carboxylic acid moiety facilitates coupling reactions and derivatization, while the fused ring system offers rigidity and defined stereochemistry. Bench-stable and compatible with common purification methods, it functions effectively in peptide-like conjugations and API intermediate construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: