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Structure of 6854-07-5
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5-Nitro-2-oxo-1,2-dihydropyridine-3-carboxylic acid features a conjugated dihydropyridine core with orthogonal electron-withdrawing groups: a nitro substituent at C5 and a carboxylic acid at C3. This combination imparts enhanced electrophilicity and metabolic stability, enabling direct incorporation into heterocyclic scaffolds. The molecule exhibits favorable solubility in polar solvents and maintains bench-stability under standard conditions, facilitating use in synthetic medicinal chemistry workflows.
5-Nitro-2-oxo-1,2-dihydropyridine-3-carboxylic acid serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted pyridine derivatives. Its nitro and carboxylic acid functionalities provide orthogonal reactivity for downstream transformations, including reduction, coupling, and cyclization reactions. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: