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Structure of 69321-56-8
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5-Bromo-2-methylbenzene-1-sulfonyl chloride features a brominated aromatic ring paired with a sulfonyl chloride group, enabling direct functionalization in electrophilic substitution reactions. The methyl substituent enhances regioselectivity, while the sulfonyl chloride moiety offers high reactivity for amide and sulfonamide synthesis under mild conditions. This bench-stable intermediate supports efficient access to bioactive sulfonamide scaffolds.
5-Bromo-2-methylbenzene-1-sulfonyl chloride serves as a versatile building block for sulfonamide synthesis, enabling efficient introduction of a brominated arylsulfonyl moiety. Its stability under standard bench conditions and compatibility with diverse nucleophiles facilitate straightforward functionalization in medicinal chemistry and agrochemical research. The ortho-methyl group enhances electronic modulation, while the reactive sulfonyl chloride functions efficiently in coupling reactions with amines and alcohols.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: