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CS-W001157 4
Total: USD 88.00

(2-Amino-5-methylphenyl)phosphonic acid

  • CAS No. 69675-98-5

  • Cat. No. CS-0058758
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2-Amino-5-methylphenyl)phosphonic acid|CS-0058758

Structure of 69675-98-5

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General Information

  • CAS No. 69675-98-5
  • Cat. No. CS-0058758
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀NO₃P
  • Molecular Weight 187.13
  • Synonym(s) None
  • SMILES CC1=CC=C(N)C(P(O)(O)=O)=C1

Description

This phosphonic acid derivative features a 2-amino-5-methylphenyl scaffold that delivers enhanced solubility and stability under standard conditions. The phosphonic moiety enables strong metal chelation, while the electron-donating methyl group modulates reactivity. This compound serves as a key intermediate in the synthesis of functionalized ligands for catalysis and materials science applications.

Application

(2-Amino-5-methylphenyl)phosphonic acid serves as a versatile building block for the synthesis of phosphonate-containing heterocycles and bioactive molecules. Its ortho-amino and methyl substituents enable directed functionalization and facilitate metal-catalyzed coupling reactions. The molecule exhibits good bench stability and tolerates common protecting groups, making it well-suited for multi-step synthetic sequences in medicinal chemistry and catalyst development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   83.55
  • LogP   0.38022
  • H_Acceptors   2
  • H_Donors   3
  • Rotatable_Bonds   1

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