Lot numbers can be found on the outside label of a product:
4-Amino-2-methoxybenzoic acid
-
CAS No. 2486-80-8
- Cat. No. CS-0150538
- Purity≥98%
- MDL No.MFCD00114479
*For research and further manufacturing use only, not for direct human use.
Structure of 2486-80-8
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 2486-80-8
- Cat. No. CS-0150538
- Purity ≥98%
- MDL No. MFCD00114479
- Storage RT, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₉NO₃
- Molecular Weight 167.16
- Synonym(s) m-Anisidine-4-carboxylic Acid
- SMILES COC1=C(C=CC(=C1)N)C(=O)O
Description
4-Amino-2-methoxybenzoic acid features a strategically positioned amino group and methoxy substituent on the aromatic ring, enabling enhanced solubility and directional reactivity. This combination supports efficient coupling in peptide synthesis and conjugation workflows, particularly where electron-donating effects and hydrogen bonding capacity are advantageous.
Application
4-Amino-2-methoxybenzoic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into diverse heterocyclic scaffolds and peptide conjugates. Its ortho-methoxy and para-amino groups provide orthogonal reactivity for selective derivatization, while the carboxylic acid facilitates amide coupling or esterification under standard conditions. The compound exhibits good bench stability and is readily purified by recrystallization, supporting scalable synthesis and integration into multi-step routes.
Synthesis
-
Route1
-
In-stock
2597-56-0 - ~97%
-
In-stock
2486-80-8
References
-
Chakravarty, Sarvajit; Dugar, Sundeep; Lu, Qing; Luedtke, Gregory R.; Mavunkel, Babu J.; Perumattam, John J.; Tester, Richland W. Patent: US2004/142940 A1, 2004 ; Location in patent: Page/Page column 69-70 ; US 20040142940 A1
-
-
Route2
-
In-stock
27492-84-8 - ~67%
-
In-stock
2486-80-8
References
-
Hewlett, William A.; De Paulis, Tomas; Mason, N. Scott; Schmidt, Dennis E.; Trivedi, Bakula L.; Zhang, Zhang-Jin; Ebert, Michael H. Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 12 p. 2079 - 2084
-
-
Route3
-
4093-29-2 - ~87%
-
In-stock
2486-80-8
References
-
Barraclough, P.; Beams, R. M.; Black, J. W.; Cambridge, D.; Collard, D.; et al. European Journal of Medicinal Chemistry, 1990 , vol. 25, # 6 p. 467 - 477
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P271-P280-P302+P352
|
|
Quality Control
Computational Chemistry Data
- TPSA 72.55
- LogP 0.9756
- H_Acceptors 3
- H_Donors 2
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 4-Amino-2-methoxybenzoic acid sigma4-Amino-2-methoxybenzoic acid manufacturer4-Amino-2-methoxybenzoic acid price4-Amino-2-methoxybenzoic acid structure4-Amino-2-methoxybenzoic acid SDSbuy 4-Amino-2-methoxybenzoic acid4-Amino-2-methoxybenzoic acid supplier4-Amino-2-methoxybenzoic acid uses4-Amino-2-methoxybenzoic acid molecular weightprice of 4-Amino-2-methoxybenzoic acid4-Amino-2-methoxybenzoic acid chemical name formula of 4-Amino-2-methoxybenzoic acid